产品货号：
Z11363
中文名称：
ATG16L1抗体
英文名称：
Anti-ATG16L1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATG16L1 Antibody |
| 指标别名 | APG16 like 1;APG16L;ATG16L;ATG16L1;Autophagy related protein 16 1;FLJ00045;FLJ10035;FLJ10828;FLJ22677;IBD10;WDR30 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | ATG16L1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATG16 antibody was raised against a 18 amino acid synthetic peptide from near the center of human ATG16.The immunogen is located within amino acids 190 - 240 of ATG16. |
| 计算分子量 | 68kDa |
| 成分 | ATG16 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATG16 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.ATG16,another member of the autophagy protein family,forms a complex with the ATG5-ATG12 conjugate.This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome.Because mammalian ATG16 has seven WD-repeats in its C-terminal domain,it has been suggested that these may form a platform for further protein-protein interactions.Multiple isoforms of ATG16 are known to exist. |
| Uniprot ID | Q676U5 |
| 基因名全称 | ATG16 autophagy related 16-like 1 (S.cerevisiae) |
| 蛋白名全称 | ATG16 autophagy related 16-like 1 (S.cerevisiae) |
| 推荐稀释比 | ATG16 antibody can be used for the detection of ATG16 by Western blot at 0.25 ～ 0.5μg/mL.Antibody can also be used for immunocytochemistry starting at 2μg/mL.For immunofluorescence start at 4μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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